Connecting you to a world of zebrafish revertible mutants

Connecting you to a world of zebrafish revertible mutants

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zfishbook connecting you to a world of zebrafish

zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.In these lines,a monomeric red fluorescent protein (mRFP) is encoded by an artificial 3 exon,resulting in a translational fusion to endogenous loci.zfishbook connecting you to a world of zebrafish zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.In these lines,a monomeric red fluorescent protein (mRFP) is encoded by an artificial 3 0 exon,resulting in a translational fusion to endogenous loci.Zebrafish approaches enhance the translational research Feb 01,2014 Connecting you to a world of zebrafish revertible mutants#0183;During the past few decades,zebrafish (Danio rerio) have been a workhorse for developmental biology and genetics.Concurrently,zebrafish have proved highly accessible and effective for translational research by providing a vertebrate animal model useful for gene discovery,disease modeling,chemical genetic screening,and other medically relevant studies.

Zebrafish approaches enhance the translational research

Feb 01,2014 Connecting you to a world of zebrafish revertible mutants#0183;During the past few decades,zebrafish (Danio rerio) have been a workhorse for developmental biology and genetics.Concurrently,zebrafish have proved highly accessible and effective for translational research by providing a vertebrate animal model useful for gene discovery,disease modeling,chemical genetic screening,and other medically relevant studies.Zebrafish abcb11b mutant reveals strategies to restore Hepatocytes of mutant zebrafish failed to excrete the fluorescently tagged bile acid that is a substrate of human BSEP.Multidrug resistance protein 1,which is thought to play a compensatory role in Abcb11 knockout mice,was mislocalized to the hepatocyte cytoplasm in abcb11b mutant zebrafish and in a patient lacking BSEP protein due to ZFIN Person Ekker,Stephen C.- Zebrafish InformationIn parallel,we engineered transposon tools for the zebrafish including protein trap gene-breaking vectors to generate a collection of molecularly characterized and revertible mutant zebrafish lines,an ongoing effort in the laboratory.Custom restriction endonucleases offer a third leg,targeted genetic modification.

ZFIN Person Ekker,Stephen C.- Zebrafish Information

In parallel,we engineered transposon tools for the zebrafish including protein trap gene-breaking vectors to generate a collection of molecularly characterized and revertible mutant zebrafish lines,an ongoing effort in the laboratory.Custom restriction endonucleases offer a third leg,targeted genetic modification.ZFIN Lab Stephen C.Ekker Laboratory - ZFIN The Zebrafish In parallel,we engineered transposon tools for the zebrafish including protein trap gene-breaking vectors to generate a collection of molecularly characterized and revertible mutant zebrafish lines,an ongoing effort in the laboratory.Custom restriction endonucleases offer a third leg,targeted genetic modification.ZFIN Lab Stephen C.Ekker Laboratory - ZFIN The Zebrafish In parallel,we engineered transposon tools for the zebrafish including protein trap gene-breaking vectors to generate a collection of molecularly characterized and revertible mutant zebrafish lines,an ongoing effort in the laboratory.Custom restriction endonucleases offer a third leg,targeted genetic modification.

Yong Tat Koh - Senior Regional Sales Engineer - Nikon

- Assisted in research projects to stain zebrafish specimens,generate and identify zebrafish mutants.- Maintained zebrafish fishlines and staged zebrafish embryos.- Micro-injected zebrafish embryos at 1-cell stage - Performed PCR for PCR cloning and identification of zebrafish mutants.- Utilized abovementioned skills to generate a zebrafish Volume 40 Issue D1 Nucleic Acids Research OxfordJan 01,2012 Connecting you to a world of zebrafish revertible mutants#0183;Crystallography Open Database (COD) an open-access collection of crystal structures and platform for world-wide collaboration Saulius Graulis ,Adriana Dakevi ,Andrius Merkys ,Daniel Chateigner ,Luca Lutterotti Volume 40 Issue D1 Nucleic Acids Research OxfordJan 01,2012 Connecting you to a world of zebrafish revertible mutants#0183;Crystallography Open Database (COD) an open-access collection of crystal structures and platform for world-wide collaboration Saulius Graulis ,Adriana Dakevi ,Andrius Merkys ,Daniel Chateigner ,Luca Lutterotti

Using Zebrafish to Analyze the Genetic and Environmental

Clark KJ,Argue DP,Petzold AM,Ekker SC.zfishbook connecting you to a world of zebrafish revertible mutants.Nucleic Acids Res.2012;40:D90711.PubMed CrossRef Google ScholarUsing Zebrafish to Analyze the Genetic and Environmental Clark KJ,Argue DP,Petzold AM,Ekker SC.zfishbook connecting you to a world of zebrafish revertible mutants.Nucleic Acids Res.2012;40:D90711.PubMed CrossRef Google ScholarTrapping Cardiac Recessive Mutants via Expression-based Feb 15,2013 Connecting you to a world of zebrafish revertible mutants#0183;The first two large-scale mutagenesis screens using ENU as a mutagen generated hundreds of mutants,which laid the foundation for the zebrafish to become a premier animal model.8,10 To address the limitations of molecular cloning,mutagens with a sequence tag have been exploited,including either retrovirus- 9,11 or transposon-based vectors

Title Senior Regional Sales EngineerLocation SingaporeConnections 18David P.Argue

David P.Argue 715 20th Ave SW 507-261-6157 Rochester,MN 55902 [email protected] EDUCATION:B.S.Computer Engineering-Iowa State UniversityAmes,IA -GPA:3.98/4.0 INTELLECTUAL PROPERTY LICENSING Zebrafish Management Software to AquaNeering 07/2012Stephen C.Ekker - PublicationsZebrafish a model for the study of addiction genetics.Human Genetics.131 977-1008.PMID 22207143 DOI 10.1007/s00439-011-1128-0 1 2012 Clark KJ,Argue DP,Petzold AM,Ekker SC.zfishbook connecting you to a world of zebrafish revertible mutants.Nucleic Acids Research.40 D907-11.PMID 22067444 DOI 10.1093/nar/gkr957 1 2011Some results are removed in response to a notice of local law requirement.For more information,please see here.Previous123456NextFAIRsharing biodbcore-000108 zfishbookzfishbook connecting you to a world of zebrafish revertible mutants.Clark KJ,Argue DP,Petzold AM,Ekker SC Nucleic Acids Res 2011 View Paper (PubMed) View Publication

Some results are removed in response to a notice of local law requirement.For more information,please see here.12345Nextzfishbook connecting you to a world of zebrafish - CORE

zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.In these lines,a monomeric red fluorescent protein (mRFP) is encoded by an artificial 3 exon,resulting in a translational fusion to endogenous loci.SCORE Imaging Specimen in a Corrected Optical Rotational Jun 08,2010 Connecting you to a world of zebrafish revertible mutants#0183;zfishbook connecting you to a world of zebrafish revertible mutants 8 November 2011 Nucleic Acids Research,Vol.40,No.D1 Fully automated cellular-resolution vertebrate screening platform with parallel animal processingMutagenesis and phenotyping resources in zebrafish for A modestly priced,concerted effort among several labs throughout the world could leverage this mutant zebrafish resource to phenotype all the genes in a vertebrate genome.Having measurable phenotypes for all zebrafish genes would have a profound effect on the field of human genetics and be a major contributor to our understanding of signals

Mutagenesis and phenotyping resources in zebrafish for

A modestly priced,concerted effort among several labs throughout the world could leverage this mutant zebrafish resource to phenotype all the genes in a vertebrate genome.Having measurable phenotypes for all zebrafish genes would have a profound effect on the field of human genetics and be a major contributor to our understanding of signals Multiplane Calcium Imaging Reveals Disrupted Development GCaMP6s fluorescence in a pcdh19 mutant 3 dpf zebrafish larva.Shown is a movie assembled from a maximum intensity projection of all imaged planes in a pcdh19 mutant 3 dpf larva.A Gaussian blur (radius = 0.5 pixels) was used here for display purposes but was not used for the analyzed data.International Zebrafish Mutagenic Protein Trap - StephenClark,Karl J; Argue,David P; Petzold,Andrew M et al.(2012) zfishbook connecting you to a world of zebrafish revertible mutants.Nucleic Acids Res 40:D907-11 Comments

Gbt1324 Gbt0309 Gbt0220 (Retired) Gbt1242 Gbt0488 Gbt0346zfishbook Connecting you to a world of zebrafish

zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.In these lines,a monomeric red fluorescent protein (mRFP) is encoded by an artificial 3 exon,resulting in a translational fusion to endogenous loci.Forward Genetic Screening Using Behavioral Tests in The zebrafish enjoys several advantages over other model organisms.It is small,easy to maintain,prolific,and numerous genetic tools are available for it.For example,forward genetic screens have allowed investigators to identify important genes potentially involved in a variety of functions from embryogenesis to cancer.However,despite its sophisticated behavioral repertoire,behavioral Forward Genetic Screening Using Behavioral Tests in The zebrafish enjoys several advantages over other model organisms.It is small,easy to maintain,prolific,and numerous genetic tools are available for it.For example,forward genetic screens have allowed investigators to identify important genes potentially involved in a variety of functions from embryogenesis to cancer.However,despite its sophisticated behavioral repertoire,behavioral

Forward Genetic Screening Using Behavioral Tests in

Oct 05,2016 Connecting you to a world of zebrafish revertible mutants#0183;Learn Mem Clark KJ,Argue DP,Petzold AM,Ekker SC (2012) zshbook 22:417425 connecting you to a world of zebrash revertible mutants.Saverino C,Gerlai R (2008) The social zebrash behavioral Nucleic Acids Res 40:D907D911 responses to conspecic,heterospecic,and computer animated Dudoit S,Yang YH,Callow MJ,Speed TP Forward Genetic Screening Using Behavioral Tests in Oct 05,2016 Connecting you to a world of zebrafish revertible mutants#0183;Learn Mem Clark KJ,Argue DP,Petzold AM,Ekker SC (2012) zshbook 22:417425 connecting you to a world of zebrash revertible mutants.Saverino C,Gerlai R (2008) The social zebrash behavioral Nucleic Acids Res 40:D907D911 responses to conspecic,heterospecic,and computer animated Dudoit S,Yang YH,Callow MJ,Speed TP Faculty Research University of Minnesota RochesterConnecting analytics and curriculum design The process and outcome of building a tool to browse data relevant to course designers.Journal of Learning Analytics.1(3):220-240. zfishbook connecting you to a world of zebrafish revertible mutants.Nucleic Acids Research.40(Database issue):D907-11.Epub 2011 Nov 8.

Faculty Research University of Minnesota Rochester

Connecting analytics and curriculum design The process and outcome of building a tool to browse data relevant to course designers.Journal of Learning Analytics.1(3):220-240. zfishbook connecting you to a world of zebrafish revertible mutants.Nucleic Acids Research.40(Database issue):D907-11.Epub 2011 Nov 8.FAIRsharing biodbcore-000108 zfishbookzfishbook connecting you to a world of zebrafish revertible mutants.Clark KJ,Argue DP,Petzold AM,Ekker SC Nucleic Acids Res 2011 View Paper (PubMed) View PublicationFAIRsharing biodbcore-000108 zfishbookzfishbook connecting you to a world of zebrafish revertible mutants.Clark KJ,Argue DP,Petzold AM,Ekker SC Nucleic Acids Res 2011 View Paper (PubMed) View Publication

David ARGUE Mayo Foundation for Medical Education and

zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.David ARGUE Mayo Foundation for Medical Education and Stephen Carl Ekker zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.In theseCited by 19Publish Year 2012Author Karl J.Clark,David P.Argue,Andrew M.Petzold,Stephen C.EkkerConnecting you to a world of zebrafish revertible mutants Connecting you to a world of zebrafish revertible mutants.Home; Lines.MN0001 to MN1000.MN0001 to MN0100.MN0001 to MN0010. We are using gene-breaking transposons to create dominantly labeled mutants in zebrafish (Sivasubbu et al.,Mech Dev 2006, (2012) zfishbook connecting you to a world of zebrafish revertible mutants Clark

Cited by 19Publish Year 2012Author Karl J.Clark,David P.Argue,Andrew M.Petzold,Stephen C.Ekker(PDF) zfishbook Connecting you to a world of zebrafish

zfishbook is an internet-based openly accessible database of revertible protein trap gene-breaking transposon (GBT) insertional mutants in the zebrafish,Danio rerio.In these lines,a monomericA genetic screen in zebrafish identifies the mutants vps18 Hepatomegaly is a sign of many liver disorders.To identify zebrafish mutants to serve as models for hepatic pathologies,we screened for hepatomegaly at day 5 of embryogenesis in 297 zebrafish lines bearing mutations in genes that are essential for embryonic development.Seven mutants were identified,and three have phenotypes resembling different liver diseases.

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